- Think MEAN:
- Early ages
- Ancestry (eg. Adopted or Ashkenazi)
- uNcommon types of cancer (pancreas, thyroid, brain, kidney, bladder, liver, lymphomas,etc)
Note: These lists do not include ALL possible ‘red flags’ that may indicate need for testing.
- Prior history of cancer, especially breast cancer, at a young age and/or bilateral.
- Multiple family members, male or female, with breast or other cancers.
- First Degree relative with breast, ovarian, or other cancer at a young age.
- History of abnormal breast biopsy such as atypia or LCIS.
- Diagnosis of triple negative breast cancer.
- Known mutation in family member.
- Risk score >20% on risk assessment.
- Ashkenazi Jewish Ancestry.
- Less than age 50 with diagnosis of colon or rectal cancer.
- Less than age 60 with specific tumor types related to Lynch Syndrome.
- Multiple types of cancer in individual or close relatives (uterine, ovarian, stomach, pancreas, kidney, etc)..
- More than 10 polyps or history of inflammatory bowel or polyposis syndrome.
Diagnosis of cancer with Gleason Score 7 or higher (high grade)
Metastatic prostate cancer.
Family history of high grade or metastatic cancer..
Family members with Breast, Ovarian, Pancreas, Melanoma, or other cancers.
Known mutation in family member.
MELANOMA (skin cancer)
- Family members, especially multiple members, with melanoma.
- Atypical moles/dysplastic nevus syndrome.
- Known FAMM (familial multiple mole and melanoma).
- Excessive radiation or toxic chemical exposures.
- Ovarian cancer at any age.
- Family history of ovarian cancer.
- Breast, Ovarian, Uterine, or other cancers related to syndromes.
- Known cancer gene mutation in family, such as BRCA, Lynch, or others.